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The intracellular targets of motion of metronidazole on anaerobes are mostly unknown. The 5-nitro team of metronidazole is lessened by metabolically Energetic anaerobes, and research have shown which the diminished form of the drug interacts with bacterial DNA.
Minimal (one)metronidazole topical will improve the stage or outcome of ethanol by lowering metabolism. Small/Importance Unfamiliar. Disulfiram-like response with oral metronidazole and Liquor; more unlikely to occur with vaginal administration due to low absorption
This document will not have all attainable Uncomfortable side effects and Other people may perhaps arise. Examine with your medical doctor for additional details about side effects.
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Hypersensitivity Reactions: Urticaria; erythematous rash; flushing; nasal congestion; dryness of the mouth, vagina, or vulva; fever; pruritus; fleeting joint pains.
METROGEL-VAGINAL affords nominal peak serum degrees and systemic publicity (AUCs) of metronidazole in comparison with 500 mg oral metronidazole dosing. While these lessen amounts of publicity are more unlikely to make the popular reactions seen with oral metronidazole, the possibility of these and also other reactions cannot be excluded presently.
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